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Chitosan Capsule In Pakistan and Dubai - The objective of this study was to estimate colon-specific insulin delivery with chitosan capsules. In vitro drug release experiments from chitosan capsules containing 5(6)-carboxyfluorescein (CF) were carried out by the Japan Pharmacopoeia (J. P.) rotating basket method with some slight modifications. The intestinal absorption of insulin was evaluated by measuring the plasma insulin levels and its hypoglycemic effects after oral administration of the chitosan capsules containing insulin and additives. Little release of CF from the capsules was observed in liquid 1, an artificial gastric juice (pH 1), or in liquid 2, an artificial intestinal juice (pH 7).
However, the release of CF was markedly increased in the presence of rat cecal contents. A marked absorption of insulin and a corresponding decrease in plasma glucose levels was observed following the oral administration of these capsules that contain 20 IU of insulin and sodium glycocholate (PA% = 3.49%), as compared with the capsules containing only lactose or only 20 IU of insulin (PA% = 1.62%). The hypoglycemic effect started from 8 h after the administration of chitosan capsules when the capsules entered the colon, as evaluated by the transit time experiments with chitosan capsules. These findings suggest that chitosan capsules may be useful carriers for the colon-specific delivery of peptides including insulin.Chitosan is extracted from shells of crabs and shrimps.
These Chitosan capsules are treated to become more edible than natural Chitin. Each capsule contains 85% Chitin, which has a structure similar to cellulose. Drasanvi capsules supply 800 mg of Chitosan per day, divided into two (2) doses.Our capsules are vegetable-based. They are manufactured from Hydroxypropyl Methylcellulose, which is a product derived from plant cellulose. Chitosan Capsule In Pakistan and Dubai. These capsules have been certified by the Vegetarian Society. Our Chitosan capsules come in blister packs. Blister packs protect products against adverse external influences that may affect its quality or potency (such as mechanical damage and environmental factors like moisture or biological contamination), ensuring their composition for extended periods of time.
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